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BAC-5 - CYTOPLASMIC DENSE FINE SPECKLED/HOMOGENEOUS STAINING PLUS NUCLEOLAR HOMOGENEOUS
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In lupus patients, anti-rRNP antibodies are associated with psychosis, liver involvement and type V glomerulonephritis; in some patients, the titer may fluctuate with disease activity.
Bonfa E, Golombek SJ, Kaufman LD, et al: Association between lupus psychosis and anti-ribosomal P protein antibodies. N Engl J Med 317:265-71, 1987.
Isshi K, Hirohata S: Differential roles of the anti-ribosomal P antibody and antineuronal antibody in the pathogenesis of central nervous system involvement in systemic lupus erythematosus. Arthritis Rheum 41:1819-27, 1998.