Relevância Clínica

AC-25 - Spindle Fibers

Relevâncias Clínicas - Primeiro nível

The AC-25 pattern has low positive predictive value for any disease
Found very infrequently in a routine serology diagnostic setting
Antigen recognized includes HsEg5; specific immunoassays for this autoantibody, or other spindle fiber targets, are currently not commercially available

Relevâncias Clínicas - Segundo nível

"While AC-25 is not associated with a defined autoimmune disease, reactivity with HsEg5 is more commonly found in SjS and SLE Note: Specific immunoassays for HsEg5 are currently not commercially available. "