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AC-25 - Spindle Fibers
Relevâncias Clínicas - Primeiro nível
The AC-25 pattern has low positive predictive value for any disease
Found very infrequently in a routine serology diagnostic setting
Antigen recognized includes HsEg5; specific immunoassays for this autoantibody, or other spindle fiber targets, are currently not commercially available
Relevâncias Clínicas - Segundo nível
"While AC-25 is not associated with a defined autoimmune disease, reactivity with HsEg5 is more commonly found in SjS and SLE Note: Specific immunoassays for HsEg5 are currently not commercially available. "