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AC-1 AC-2 AC-3 AC-4 AC-5 AC-6 AC-7 AC-8 AC-9
AC-10
AC-11 AC-12 AC-13 AC-14 AC-15 AC-16 AC-17 AC-18 AC-19 AC-20 AC-21 AC-22 AC-23 AC-24 AC-25 AC-26 AC-27 AC-28 AC-29
BAC-1 BAC-2 BAC-3 BAC-4 BAC-5

AC-10 - Punctate Nucleolar

Relevâncias Clínicas - Primeiro nível

The AC-10 pattern can be seen in various conditions, including SSc, Raynaud’s phenomenon, SjS, and cancer.
Reimer, Rose, Scheer et al., 1987
Kuwana, Kaburaki, Mimori et al., 1993
Fritzler, von Munlen, Toffoli et al., 1995
Fujii, Mimori & Akizuki, 1995
Imai, Ochs, Kiyosawa et al., 1996
If the AC-10 pattern is observed in the serum of patients with conditions mentioned above, follow-up testing for anti-NOR90 (hUBF) antibodies is to be considered; the antigen is included in disease specific immunoassays (i.e. SSc profile).
Fritzler, von Munlen, Toffoli et al., 1995
Fujii, Mimori & Akizuki, 1995
While AC-10 is associated with anti-RNApol I antibodies, these antibodies almost always coexist with anti-RNApol III antibodies which reveal the AC-5 pattern; therefore, if SSc is clinically suspected, it is recommended to perform a follow-up test for anti-RNApol III antibodies (See also AC-5); specific immunoassays for anti-RNA pol I antibodies are currently not commercially available.
Reimer, Rose, Scheer et al., 1987
Kuwana, Kaburaki, Mimori et al., 1993
Yamasaki, Honkanen-Scott, Hernandez et al., 2006