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AC-28 - Mitotic Chromosomal
Relevancias Clinicas - Primer nivel
Found very infrequently in a routine serology diagnostic setting
Antigens recognized include DCA, MCA1, and MCA5; specific immunoassays for these autoantibodies are currently not commercially available
The AC-28 pattern has low positive predictive value for any disease
Relevancias Clinicas - Segundo nivel
Autoantibodies to DCA have been described in patients with SLE
Autoantibodies to MCA1 have been described in patients with carcinoma
Autoantibodies to MCA5 have been described in patients with discoid lupus erythematosus, chronic lymphocytic leukemia, SjS, and polymyalgia rheumatica
Specific immunoassays for these autoantibodies are currently not commercially available.