entre
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cadastre-se

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AC-1 AC-2 AC-3 AC-4 AC-5 AC-6 AC-7 AC-8 AC-9 AC-10 AC-11 AC-12 AC-13 AC-14 AC-15 AC-16 AC-17 AC-18 AC-19 AC-20 AC-21
AC-22
AC-23 AC-24 AC-25 AC-26 AC-27 AC-28 AC-29
BAC-1 BAC-2 BAC-3 BAC-4 BAC-5

AC-22 - POLAR/GOLGI-like

Relevâncias Clínicas - Primeiro nível

Found in small numbers of patients with a variety of conditions
Stinton et al., 2004
Antigens recognized include giantin/macrogolgin and distinct golgin molecules; specific immunoassays to detect autoantibodies directed to specific Golgi antigens are currently not commercially available
Covini et al., 2012
Calise et al., 2015
Novembrino et al., 2014
Keppeke et al., 2016

Relevâncias Clínicas - Segundo nível

The AC-22 pattern has been reported in small numbers of patients with a variety of conditions, including SjS, SLE, RA, MCTD, GPA, idiopathic cerebellar ataxia, paraneoplastic cerebellar degeneration, adult Still’s disease, and viral infections including HIV and EBV
Stinton et al., 2004
Fritzler et al., 1984
Vermeersch et al., 2003
Staub et al., 2003
Although possibly biased by the referral pattern, one study concluded that the AC-22 pattern is not clinically associated with SARD as there were only 1 SjS and 2 RA diagnoses among their 20 AC-22 positive cases collected over 10-years and a clinical follow-up observation ranging from 0 – 10 years; the remaining cases showed diverse diagnoses including 2 carcinomas
Vermeersch et al., 2011
The AC-22 pattern is rare in the general population
Satoh et al., 2012