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  • BAC-5 - CYTOPLASMIC DENSE FINE SPECKLED/HOMOGENEOUS STAINING PLUS NUCLEOLAR HOMOGENEOUS
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BAC-5

BAC-5 - CYTOPLASMIC DENSE FINE SPECKLED/HOMOGENEOUS STAINING PLUS NUCLEOLAR HOMOGENEOUS

Descrição

Nucleoli with weak homogeneous fluorescence or negative. The cytoplasm expresses intense fine dense (tending to homogeneous) speckled staining. Negative nuclei and mitotic cells.

Associação Antigênica

Anti-rRNP (ribosomal antiprotein P)

Doenças Associadas

Systemic lupus erythematosus

Relevâncias Clínicas - Primeiro nível

In lupus patients, anti-rRNP antibodies are associated with psychosis, liver involvement and type V glomerulonephritis; in some patients, the titer may fluctuate with disease activity.
Bonfa E, Golombek SJ, Kaufman LD, et al: Association between lupus psychosis and anti-ribosomal P protein antibodies. N Engl J Med 317:265-71, 1987.
Isshi K, Hirohata S: Differential roles of the anti-ribosomal P antibody and antineuronal antibody in the pathogenesis of central nervous system involvement in systemic lupus erythematosus. Arthritis Rheum 41:1819-27, 1998.

Referências

Bonfa E, Golombek SJ, Kaufman LD, et al: Association between lupus psychosis and anti-ribosomal P protein antibodies. N Engl J Med 317:265-71, 1987. Isshi K, Hirohata S: Differential roles of the anti-ribosomal P antibody and antineuronal antibody in the pathogenesis of central nervous system involvement in systemic lupus erythematosus. Arthritis Rheum 41:1819-27, 1998.