entre
ou
cadastre-se

Padrões

  • início
  • Padrões
  • BAC-2 - NUCLEAR COARSE SPECKLED PLUS NUCLEOLAR HOMOGENEOUS WITH PERIPHERAL STAINING OF THE METAPHASE PLATE (NON-STAINED CHROMOSOMES)
AC-1 AC-2 AC-3 AC-4 AC-5 AC-6 AC-7 AC-8 AC-9 AC-10 AC-11 AC-12 AC-13 AC-14 AC-15 AC-16 AC-17 AC-18 AC-19 AC-20 AC-21 AC-22 AC-23 AC-24 AC-25 AC-26 AC-27 AC-28 AC-29
BAC-1
BAC-2
BAC-3 BAC-4 BAC-5

BAC-2 - NUCLEAR COARSE SPECKLED PLUS NUCLEOLAR HOMOGENEOUS WITH PERIPHERAL STAINING OF THE METAPHASE PLATE (NON-STAINED CHROMOSOMES)

Descrição

Cells in interphase with strong nuclear fine speckled staining, weak and inconstant nucleolar homogeneous staining, metaphase cells with fluorescent decoration around the metaphase plate.

Associação Antigênica

Anti-Ku

Doenças Associadas

Systemic Sclerosis/Polymyositis overlap, Systemic Lupus Erythematosus and Scleroderma.

Relevâncias Clínicas - Primeiro nível

Autoantibodies to Ku are associated with SSc-AIM and SLE-SSc-AIM overlap syndromes
Betteridge Z & McHugh N., 2016
Dellavance, Gabriel Júnior, Cintra et al., 2003
Francoeur AM, Peebles CL, Gompper PT, Tan EM. 1986
Franceschini F, Cavazzana I, Generali D., 2002
Ho KT, Reveille JD., 2003
Takeda Y, Dynan WS, 2001

Referências

Betteridge Z, McHugh N. Myositis-specific autoantibodies: an important tool to support diagnosis of myositis. J Intern Med 2016;280:8–23. Dellavance Alessandra, Gabriel Júnior Alexandre, Cintra Alice F. U., Ximenes Antônio Carlos, Nuccitelli Barbara, Taliberti Ben Hur et al . II Consenso Brasileiro de Fator Antinuclear em Células HEp-2: Definições para a padronização da pesquisa de auto-anticorpos contra constituintes do núcleo (FAN HEp-2), nucléolo, citoplasma e aparelho mitótico e suas associações clínicas. Rev. Bras. Reumatol. 2003 43( 3 ): 129-140. Francoeur AM, Peebles CL, Gompper PT, Tan EM: Indentification of Ki (Ku 70-80) autoantigens and analysis of anti-Ki autoantibody reactivity. J Immunol 1986; 136:1648-53. Franceschini F, Cavazzana I, Generali D. Anti-Ku in connective tissue disease: clinical and serological evaluation of 14 patients. J Rheumatol. 2002;29:1393–1397. Ho KT, Reveille JD. The clinical relevance of autoantibodies in scleroderma. Arthritis Res Ther. 2003;5(2):80-93. Takeda Y, Dynan WS. Autoantibodies against DNA double-strand break repair proteins. Front Biosci. 2001;6:1412–1422.