entre
ou
cadastre-se

Padrões

AC-1 AC-2 AC-3 AC-4 AC-5 AC-6 AC-7 AC-8 AC-9 AC-10 AC-11 AC-12 AC-13 AC-14 AC-15 AC-16 AC-17 AC-18 AC-19 AC-20 AC-21 AC-22 AC-23 AC-24 AC-25 AC-26 AC-27 AC-28 AC-29
BAC-1 BAC-2
BAC-3
BAC-4 BAC-5

BAC-3 - NUCLEAR QUASI-HOMOGENEOUS SPECKLED

Descrição

Extremely fine specked nuclear fluorescence, approaching the homogeneous texture, with the metaphase plate similarly stained.

Associação Antigênica

Miscellaneous antigenic targets are recognized, including chromatin antigens (native DNA, nucleosome, histones), however with lower frequency as compared to the nuclear homogeneous pattern.

Doenças Associadas

Non specific

Relevâncias Clínicas - Primeiro nível

Demands further investigation, because it can be related to systemic autoimmune rheumatic diseases (SARD). However, the association with SARD is much weaker than that observed with the nuclear homogeneous pattern.
Franca NR, Dellavance, A Rodrigues SH., 2011
Mariz HA, Sato EI, Barbosa SH, et al., 2011.
Francescantonio, Cruvinel, Dellavance et al. 2014.

Referências

Franca NR, Dellavance, Alessandra Rodrigues SH, Perazzio SF, Silva NP, Andrade LEC. Quasi-homogeneous ANA-HEp-2 pattern reflects an autoantibody profile intermediat the homogeneous and dense fine speckled nuclear patterns. Arthritis Rheum. 2011;63 Suppl(10):2307. Mariz HA, Sato EI, Barbosa SH, Rodrigues SH, Dellavance A, Andrade LEC. Pattern on the antinuclear antibody-HEp-2 test is a critical parameter for discriminating antinuclear antibody-positive healthy individuals and patients with autoimmune rheumatic diseases. Arthritis Rheum. 2011 Jan;63(1):191–2 Francescantonio Paulo Luiz Carvalho, Cruvinel Wilson de Melo, Dellavance Alessandra, et al . IV Consenso Brasileiro para pesquisa de autoanticorpos em células HEp-2. Rev. Bras. Reumatol. 2014; 54(1): 44-50.